MIKULSKI, COLLINS PRAISE SENATE PASSAGE OF BIPARTISAN RESOLUTION INTRODUCED BY ALL 20 SENATE WOMEN COMMEMORATING THE 25TH ANNIVERSARY OF NIH’S OFFICE OF RESEARCH ON WOMEN’S HEALTH

Video of Senator Collins’ remarks is available – here.

WASHINGTONU.S. Senators Barbara A. Mikulski (D-Md.) and Susan Collins (R-Maine), senior members of the Senate Health, Education, Labor and Pensions (HELP) Committee, today praised Senate passage of their bipartisan resolution cosponsored by all 20 Senate women to commemorate the 25th anniversary of the National Institutes of Health’s (NIH) Office of Research on Women’s Health (ORWH). September 10, 2015 marked the 25th anniversary of the establishment of the ORWH.

"For far too long, women were being excluded from clinical research trials and women’s health issues were being ignored,” Senator Mikulski said. “Twenty-five years ago, women did not have much to celebrate when it came to scientific advances – we weren’t even at the table. Now researchers look at disease in a gender-specific way, and we've made great strides in breast cancer and cervical cancer research, AIDS research, and mapping the human genome. We’ve changed that paradigm, but we’re not done yet. We must continue to raise awareness, raise consciousness and raise hell so that women are not left behind when it comes to their health.”

 “For the last twenty-five years, the NIH Office of Research on Women’s Health (ORWH) has led the charge in increasing scientific understanding and personalized treatment for women across the country and around the world,” said Senator Collins. “I am pleased to join with Senator Mikulski in leading this bipartisan resolution that honors this important milestone and champions the continued importance of the inclusion of women’s health in NIH research.”

Senators Mikulski and Collins are longtime advocates of women’s health and supporters of scientific research. In 1990, Senator Mikulski and a group of her women colleagues drove together to NIH in Bethesda, Maryland. Their goal was to assemble key government health officials to address concerns regarding women’s exclusion from clinical research. As a result of this meeting, Senator Mikulski and her colleagues were able to build support for the ORWH and successfully worked to establish and fund the Office at NIH.

The ORWH has made significant progress in developing and implementing policies to ensure the inclusion of women in NIH clinical research. The Office’s research efforts benefit all individuals with diseases and disorders studied by researchers, including men, women, older and younger adults, children and minority populations. ORWH-supported research has dramatically increased understanding of the importance of gender specific research, and has spurred policy change and programs focused on the health of girls, women and their families.

Today, more than half of participants in NIH-funded clinical trials are women. The ORWH now works in partnership with NIH’s 27 Institutes and Centers to ensure that women’s health research continues to be a part of the scientific framework at NIH and throughout the scientific community.

In addition to Senators Mikulski and Collins, the bipartisan resolution is cosponsored by Senators Kelly Ayotte (R-N.H.), Tammy Baldwin (D-Wis.), Barbara Boxer (D-Calif.), Maria Cantwell (D-Wash.), Joni Ernst (R-Iowa), Shelley Moore Capito (R-W.Va.), Deb Fischer (R-Nebraska), Dianne Feinstein (D-Calif.), Kirsten Gillibrand (D-N.Y.), Heidi Heitkamp (D-N.D.), Mazie Hirono (D-Hawaii), Amy Klobuchar (D-Minn.), Claire McCaskill (D-Mo.), Lisa Murkowski (R-Alaska), Patty Murray (D-Wash.), Jeanne Shaheen (D-N.H.), Debbie Stabenow (D-Mich.) and Elizabeth Warren (D-Mass.).

 

The text of the bipartisan resolution, follows:

Celebrating the 25th anniversary of the Office of Research on Women's Health at the National Institutes of Health.

Whereas, on September 10, 1990, the Office of Research on Women's Health (in this resolution referred to as `ORWH') was established at the National Institutes of Health (in this resolution referred to as `NIH') to--

(1) ensure that women were included in NIH-funded clinical research;

(2) set research priorities to address gaps in scientific knowledge; and

(3) promote biomedical research careers for women;

Whereas ORWH was established in law by the National Institutes of Health Revitalization Act of 1993 (Public Law 103-43; 107 Stat. 122) and implemented the law requiring researchers to include women in NIH-funded tests of new drugs and other clinical trials;

Whereas, today, more than 1/2 of the participants in NIH-funded clinical trials are women, enabling the development of clinical approaches to prevention, diagnosis, or treatment appropriate for women;

Whereas, in 2015, ORWH, with enthusiastic support from NIH leadership, announced that, beginning in January 2016, NIH-funded scientists must account for the possible role of sex as a biological variable in vertebrate animal and human studies;

Whereas ORWH, along with NIH leadership, enhances awareness of the need to adhere to principles of rigor and transparency, including the need to publish sex-specific results to inform the treatment of women, men, boys, and girls;

Whereas, over the past 25 years, ORWH has helped expand research on women's health beyond its roots in reproductive health to include--

(1) the study of the health of women across the lifespans of women; and

(2) biomedical and behavioral research from cells to selves;

Whereas, by studying both sexes, ORWH is leading the scientific community to make discoveries headed toward treatments that are more personalized for both women and men;

Whereas, today, ORWH communicates through programs and policies that sex and gender affect health, wellness, and how diseases progress;

Whereas turning discovery into health for all, the NIH motto, means studying both females and males across the biomedical research continuum;

Whereas the ORWH Specialized Centers of Research on Sex Differences program supports established scientists who do basic, clinical, and translational research with a sex and gender focus;

Whereas all NIH Institutes and Centers fund and encourage scientists at universities across the Nation to conduct research on the health of women and on sex and gender influences;

Whereas, over the past 25 years, ORWH has established several career-enhancement initiatives for women in biomedicine, including the Building Interdisciplinary Research Careers in Women's Health program that connects junior faculty with mentors who share interests in women's health research;

Whereas ORWH co-directs the NIH Working Group on Women in Biomedical Careers, which develops and evaluates policies to promote the recruitment, retention, and sustained advancement of women scientists;

Whereas the Women's Health Initiative (in this resolution referred to as `WHI') marked the first long-term study of its kind and resulted in a wealth of information so that women and their physicians can make more informed decisions regarding postmenopausal hormone therapy;

Whereas WHI reduced the incidence of breast cancer by 10,000 to 15,000 cases per year, and the overall health care savings far exceeded the WHI investment;

Whereas ORWH supported the National Cancer Institute's development of a vaccine that prevents the transmission of Human Papilloma Virus, resulting in a decrease in the number of cases of cervical cancer;

Whereas, in 1994, ORWH co-sponsored with the National Institute of Allergy and Infectious Diseases a landmark study, the results of which showed that giving the drug AZT to HIV-infected women with little or no prior antiretroviral therapy reduced the risk of mother-to-child transmission of HIV by 2/3 ;

Whereas, according to the Centers for Disease Control and Prevention (CDC), perinatal HIV infections in the United States have dropped by more than 90 percent;

Whereas ORWH co-funded a large clinical study of the genetic and environmental risk factors for ischemic stroke, which identified a strong relationship between the number of cigarettes smoked per day and the probability of ischemic stroke in young women, prompting the targeting of smoking as a preventable and modifiable risk factor for cerebrovascular disease in young women; and

Whereas, over the past 25 years, ORWH has contributed support toward major advances in knowledge about the genetic risk for breast cancer, and discovery of the BRCA1 and BRCA2 genetic risk markers has enabled better-informed genetic counseling and treatment for members of families that carry mutant alleles: Now, therefore, be it

Resolved, That the Senate –

(1) commends ORWH for its work over the past 25 years to improve and save the lives of women worldwide and expresses that ORWH must remain intact for this and future generations;

(2) recognizes that there remain striking sex and gender differences among many diseases and conditions on which ORWH should continue to focus;

(3) encourages ORWH to continue to focus on ensuring that the NIH supports biomedical research that considers sex as a biological variable across the research spectrum; and

(4) encourages the Director of the NIH  to continue to consult and involve the ORWH on all matters related to the influence of sex and gender on health, especially those pertaining to the consideration of sex as a biological variable in research with vertebrate animals and humans.